Hangzhou Jinlan Pharm-Drugs Technology Co. Ltd.(JL Pharm) is an advanced pharmaceutical corporation with a laboratory of 1200 square meters in Nanjing city, and cooperative GMP production plants in Beljing, Jiangsu, Zhejiang, Jiangxi, Chengdrand Shandong.We can provide both CDMO technology research and development services, and a ful range of laboratory R&D and production services for raw materials and pharmaceutical intermediates to globapharmaceutical companies during which synthetic route research and development, process reearch and development and optimization, scale-up production, domestic and foreign drug registration, and industrial equipment selection, automatic control system and technical process packages.
Product Name:
5-Aminosalicylic acid
Synonyms:
5-Aminosalicylic acid, 98.5%, IKK inhibitor;
2-HYDROXY-5-AMINOBENZOIC ACID;
3-Carboxy-4-hydroxyaniline;
5-AMINO-2-HYDROXYBENZOIC ACID;
5-AMINOSALICYLIC ACID;
5-ASA;5-AS;
rowasa
CAS: |
89-57-6 |
MF: |
C7H7NO3 |
MW: |
153.14 |
EINECS: |
201-919-1 |
Product Categories: |
API;CITANEST;Pharmaceuticals;Carboxylic Acids;Aromatics;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Carboxylic Acids;Phenyls & Phenyl-Het;Organic acids;Various Metabolites and Impurities;Fendosal;Intermediates & Fine Chemicals;Phenyls & Phenyl-Het;Fluorescent;FINE Chemical & INTERMEDIATES;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Metabolites & Impurities |
Mol File: |
89-57-6.mol |
Melting point |
275-280 °C (dec.) (lit.) |
Boiling point |
276.03°C (rough estimate) |
density |
1.3585 (rough estimate) |
vapor pressure |
0Pa at 25ºC |
refractive index |
1.5500 (estimate) |
Fp |
279-281°C |
storage temp. |
2-8°C |
solubility |
Soluble in dimethyl sulfoxide. |
pka |
2.74, 5.84(at 25ºC) |
form |
tablets |
color |
off-white to gray |
PH |
4.0-4.1 (0.8g/l, H2O, 20ºC) |
PH Range |
Non-B uorescence (3.1) to light green B uorescence (4.4) |
Water Solubility |
<0.1 g/100 mL at 21 ºC |
Decomposition |
279-281 ºC |
Merck |
14,5904 |
BRN |
2090421 |
BCS Class |
4 |
Stability: |
Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents. |
Major Application |
Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis |
InChIKey |
KBOPZPXVLCULAV-UHFFFAOYSA-N |
LogP |
0.98 at 25ºC |
CAS DataBase Reference |
89-57-6(CAS DataBase Reference) |
NIST Chemistry Reference |
Mesalamine(89-57-6) |
EPA Substance Registry System |
Benzoic acid, 5-amino-2-hydroxy- (89-57-6) |