Our Advantages
Hangzhou Jinlan Pharm-Drugs Technology Co. Ltd.(JL Pharm) is an advanced pharmaceutical corporation with a laboratory of 1200 square meters in Nanjing city, and cooperative GMP production plants in Beljing, Jiangsu, Zhejiang, Jiangxi, Chengdrand Shandong.We can provide both CDMO technology research and development services, and a ful range of laboratory R&D and production services for raw materials and pharmaceutical intermediates to globapharmaceutical companies during which synthetic route research and development, process reearch and development and optimization, scale-up production, domestic and foreign drug registration, and industrial equipment selection, automatic control system and technical process packages.
Packaging & Shipping
Product Description
Product Name: Semaglutide
| CAS: |
910463-68-2 |
| MF: |
C187H291N45O59 |
| MW: |
4113.57754 |
| EINECS: |
203-405-2 |
| Product Categories: |
GLP;PP;APIs;API;910463-68-2;GLP-1 |
| Mol File: |
910463-68-2.mol |
| Semaglutide Chemical Properties |
| storage temp. |
Store at -20°C |
| solubility |
DMSO:3mg/mL (0.73 mM) |
| InChIKey |
DLSWIYLPEUIQAV-CCUURXOWSA-N |
Synonyms:
1,Sermaglutide;Semaglutide impurity;
2,Sermaglutide USP/EP/BP;
3,semaglutide;
4,Sermaglutide CAS 910463 68 2;
5,Semaglutide (H-7894.0001)
Uses: Semaglutide is used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity. It also works by slowing the movement of food through the stomach and may decrease appetite and cause weight loss. There have been no published reports of hepatotoxicity attributed to semaglutide therapy.
Mechanism of action : Semaglutide is a glucagon-like peptide-1 receptor agonist. It increases the production of a hormone that lowers the blood sugar level. It also appears to enhance growth of β cells in the pancreas, which are the sites of production. It also inhibits glucagon, which is a hormone that increases blood sugar. It additionally reduces food intake by lowering appetite and slows down digestion in the stomach. In this way it reduces body fat.
Amino acid analysis
| Asp |
0.9-1.1 |
0.9 |
| Ser |
2.1-3.9 |
2.6 |
| Glu |
4.5-5.5 |
5.1 |
| Gly |
3.6-4.4 |
4.0 |
| His |
0.9-1.1 |
1.0 |
| Arg |
1.8-2.2 |
2.1 |
| Thr |
1.8-2.2 |
2.0 |
| Ala |
2.7-3.3 |
3.0 |
| Aib |
0.7-1.3 |
1.1 |
| Tyr |
0.9-1.1 |
1.0 |
| Val |
1.8-2.2 |
2.2 |
| Lys |
0.9-1.1 |
1.0 |
| Ile |
0.9-1.1 |
1.0 |
| Leu |
1.8-2.2 |
2.1 |
| Phe |
1.8-2.2 |
2.1 |
| Trp |
Present |
Present |
| Sodium ion |
1.0%~3.0% |
2.1% |
| Carbonate |
≤0.50% |
0.09% |
| Acetic acid |
≤0.50% |
N.D |
| Trifluoroacetc acid |
≤0.25% |
N.D. |
| Related Substance |
G06-IM60 |
≤0.2% |
0.08% |
| |
G06-IM01 |
≤0.2% |
0.07% |
| |
G06-1M59 |
≤0.2% |
0.06% |
| |
G06-IM28 |
≤0.2% |
0.08% |
| |
G06-IM03 |
≤0.2% |
0.07% |
| |
Any other Unknown individual impurity |
≤0.1% |
N.D. |
| |
Total Impurities |
≤2.0% |
0.29% |
| Residue solvents |
Acetonitrle |
≤410ppm |
N.D. |
| |
Triethylamie |
≤5000ppm |
17 ppm |
| |
NN'-Diisopropylcarbodiimide |
≤100ppm |
N.D. |
| Polymer |
≤0.5% |
0.03% |
| Bacterial endotoxins |
<10EU/mg |
<10EU/mg |
Microbial limit
|
Total aerobic microbial count |
≤102cfu/g |
<10 cfu/g |
| |
Total yeast and mold count |
≤102cfu/g |
<10 cfu/g |
| |
Escherichia coli |
Absent |
N.D. |
| Peptide content |
≥80.0% |
93.5% |
| Assay(on anhydrous and salt free substance basis) |
95.0%-105.0% |
99.3% |
Detailed Photos
| Name |
Auto Injector |
| Dose |
1ml/2.25ml |
| feedback |
Visual/auditory |
| Syringe categories |
Staked-in Needle Glass Syringe |
| Rigid needle shield |
√ |
| Mode of injection |
Automatic |
| Injection area |
subcutaneous injection |
Pen Injector is a portable disposable variable dose injection pen used for insuln and other multi dose therapies, avoiding the impact of product aging on drug injection accuracy caused by long-term repeated use. It provides users with a comfortable operating experience while increasing safety technical support.
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